Jumonji domain‐containing protein 6 protein and its role in cancer
نویسندگان
چکیده
منابع مشابه
Jumonji/Arid1b (Jarid1b) protein modulates human esophageal cancer cell growth
Although esophageal cancer is highly heterogeneous and the involvement of epigenetic regulation of cancer stem cells is highly suspected, the biological significance of epigenetically modified molecules that regulate different subpopulations remains to be firmly established. Using esophageal cancer cells, we investigated the functional roles of the H3K4 demethylase Jumonji/Arid1b (Jarid1b) (Kdm...
متن کاملRoles of Protein Arginine Methyltransferase 7 and Jumonji Domain-Containing Protein 6 in Adipocyte Differentiation: A Dissertation
Regulation of gene expression comprises a wide range of mechanisms that control the abundance of gene products in response to environmental and developmental changes. These biological processes can be modulated by posttranslational modifications including arginine methylation. Among the enzymes that catalyze the methylation, protein arginine methyltransferase 7 (PRMT7) is known to modify histon...
متن کاملDebaryomyces hansenii colonization and its protein profile in psoriasis
Background: Psoriasis is an immune mediated skin disorderwhich is mainly characterized by abnormal proliferation anddifferentiation of keratinocytes. It is believed that Debaryomyceshansenii (Candida famata) can colonize skin and mucous membranesof psoriatic patients and exacerbate psoriatic lesions via toxins,antigens, and proteins. The aims of this study were to evaluateDebaryomyces hansenii ...
متن کاملThe role of Musashi protein in spermatogenesis and male infertility
Background: Inactivation of transcription occurs during two phases of spermatogenesis. First, in spermatocytes entering the primary meiosis and the second in round and elongating spermatids. These stages of inactivated transcription demand extensive regulation of translation. Therefore, presence of the control on gene expression during spermatogenesis seems essential. In the cases that post-tra...
متن کاملTranscriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6
Jumonji domain-containing protein 6 (JMJD6) is a nuclear protein involved in histone modification, transcription and RNA processing. Although JMJD6 is crucial for tissue development, the link between its molecular functions and its roles in any given differentiation process is unknown. We report that JMJD6 is required for adipogenic gene expression and differentiation in a manner independent of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Proliferation
سال: 2020
ISSN: 0960-7722,1365-2184
DOI: 10.1111/cpr.12747